Are We Doing Enough to Prepare for the NEXT PANDEMIC?

[Hawk_82]

In 2012, 6 miners in China got sick with a coronavirus and 3 of them died. They determined that the virus was able to travel from bats to humans, but not from human to human. The "bat lady" who is now the lead coronavirus researcher in the world works in the Wuhan Institute of Virology and she visited the mine where the 6 people became sick. She took samples from the mine and this is where RaTG13 (which is the closest coronavirus to Covid) was found.

Since the miners were able to get sick from the bats, but they did not pass the virus from human to human, this became the area of research. Can they do gain of function to make a coronavirus able to pass from human to human. There are published papers about adding the ACE2 receptor to a coronavirus (see research above).

 

[thewop]

In Nate Silver's book On the Edge he points out that in its 2022-23 budget, Congress allocated roughly $2 billion to prevent future pandemic.
Meanwhile, COVID killed over 1 million Americans, and cost the US economy an estimated $14 trillion.

I don't know if that $2 billion was intended to continue every year, or was one of those ten-year totals politicians like to toss around to make the numbers sound bigger.

Is $2 billion enough? Too much?

If we ignore the COVID alarmists next time it won't cost $14 trillion

 

[Aardvark86]

@SI_NYC, see below.

We’re smart enough to modify viruses so they’re infectious to humans.

But some of us aren’t smart enough to not do that.

Tabak confirmed Thursday that the NIAID did indeed fund gain-of-function research on coronaviruses in Wuhan through EcoHealth Alliance according to the colloquial understanding.

According to the policy in place from 2014 to 2018 — the “U.S. Government Gain-of-Function Deliberative Process and Research Funding Pause on Selected Gain-of-Function Research Involving Influenza, MERS, and SARS viruses” — the definition of gain-of-function research at the time of the experimentsinvolving the Wuhan Institute of Virology included “research that improves the ability of a pathogen to cause disease.”

Grant reports demonstrate that “chimeric” or combined coronaviruses studied by EcoHealth and the Wuhan Institute of Virology caused more severe disease in mice engineered to express human receptors than the backbone virus.

However, Tabak downplayed the risk posed by these chimeric viruses because they were bat coronaviruses, though the public literature described one of these viruses as “poised for human emergence.”

Fauci repeatedly denied that NIAID funded gain-of-function research in Wuhan in high-profile exchanges with Sen. Rand Paul, R-Ky., in 2021.

“Sen. Paul, you do not know what you are talking about, quite frankly, and I want to say that officially,” Fauci said in a July 2021 hearing.

Tabak confirmed in the hearing Wednesday that in October 2021 the NIH communications office changed the definition of “gain-of-function research” on the NIH website.

****

They were modifying animal viruses to be contagious in humans.
From EcoHealth's website:

https://www.ecohealthalliance.org/w...5/Text-of-Renewal-Grant-–-NIH-R01AI110964-.pdf

What do you think this experiment is trying to do:

3.3 Virus characterization: 3.3.a Construction of chimeric SARSr-CoV viruses: Infectious clones with the S gene of novel SARSr-CoVs and the SARSr-CoV WIV1 genome backbone using the reverse genetic system developed in our previous R01 (24). The correct infectious BAC clones will be screened by BAC DNA digestion with appropriate restriction enzyme or PCR amplification. The chimeric viruses will be rescued in Vero cells and then verified by sequence analyses. Our research group is well versed in coronavirus reverse genetics.
...
3.3.b Primary human airway epithelial cell culture: Primary human ciliated airway epithelial cells (HAE)cultures from the lungs of transplant recipients represent highly differentiated human airway epithelium containing ciliated and non-ciliated epithelial and goblet cells, grown on an air-liquid interface for several weeks prior to use (18, 55, 56). We will prepare HAE cultures from three different patient codes in triplicate in collaboration with the tissue procurement facility at the Cystic Fibrosis Center at UNC. Cultures will be inoculated with chimeric bat SARSr-CoVs to assess efficient replication. A
...
3.3.c Humanized mouse infection experiments: Briefly, in BSL3, n=5 10- to 20-week old hACE2 transgenic mice will be intranasally inoculated with 1 x 104 PFU of wildtype WIV-1 or chimeric bat SARSr-CoVs with different spike proteins, then monitored daily for weight loss, morbidity, and clinical signs of disease.


https://www.jax.org/strain/034860#

K18-hACE2 transgenic mice express human ACE2, the receptor used by severe acute respiratory syndrome coronavirus (SARS-CoV) to gain cellular entry. The human keratin 18 promoter directs expression to epithelia, including airway epithelia where infections typically begin. Because K18-hACE2 are susceptible to SARS-CoV-2 and SARS-CoV viruses, they are useful for studying antiviral therapies to COVID-19 and SARS.

Eye roll emoji

 

[What Would Jesus Do?]

Well, no.

First, I don't want tom to die.

Second, as smart as we all think we are, we are not so smart as to be masters of the universe when it comes to things like stopping viruses, bacteria, natural disasters, and their ilk. So, I just don't buy the concept of human blame for this sort of thing - at best, all we can ever really do is react to them. (Consider, for example, what an inexact science even the seasonal flu vaccine is as a prophylactic meashre.) Just as they did this time, viruses run their course, exact their toll, and mutate.

Sounds like you're leaving the "therefore we shouldn't do anything" part for us to infer. If you don't want us to think that's your stance, you should say so clearly. Otherwise that's your stance.

 

[seminole97]

Eye roll emoji

Why do you eyeroll at the reality? That's EcoHealth's grant application describing their gain of function research.
NIH has come clean.
It went overseas because DARPA said, 'woah, that shit's too dangerous for us.'

Seriously, what is your investment in the Chicom cover story about the wet market in Wuhan?

 

[What Would Jesus Do?]

No the information is out there. Those important people you talk about knew it. They just lied about it until people stopped caring. Your lack of knowing what information was out there proves their lying has worked.

I've linked actual, respected doctors and scientists discussing this. You've been duped. If you want to be right, inform yourself from better sources.

 

[Hawk_82]

I've linked actual, respected doctors and scientists discussing this. You've been duped. If you want to be right, inform yourself from better sources.

Can you make sense of the information that I shared and also that @seminole97 posted? Do you think those are all just coincidences?

 

[seminole97]

I've linked actual, respected doctors and scientists discussing this. You've been duped. If you want to be right, inform yourself from better sources.

Do you think the President of EcoHealth Alliance, the ones funding the research in Wuhan to make the corona viruses transmissible to humans, took part in the WHO trip to Wuhan as an impartial observer, with no conflict of interest?

They duped you by not mentioning his involvement in that research, at that site.

The alleged conflict of interest stems from the connection one of the investigators, a British zoologist and EcoHealth Alliance President Dr. Peter Daszak has with the Wuhan Institute of Virology (WIV). According to The Wall Street Journal, Dr. Daszak has worked closely with a leading virologist at WIV, Dr. Shi Zhengli on the study of bat viruses, which from 2014, was in part funded by US government grants. The institute is located just a few miles away from the wet market where Chinese authorities say SARS-CoV-2 first emerged.

 

[What Would Jesus Do?]

Can you make sense of the information that I shared and also that @seminole97 posted? Do you think those are all just coincidences?

Coincidences? No. This is part of a deliberate attempt to discredit (and eventually defund or dismantle) science and honest reporting in America. Have you been living under a rock?

 

[What Would Jesus Do?]

Do you think the President of EcoHealth Alliance, the ones funding the research in Wuhan to make the corona viruses transmissible to humans, took part in the WHO trip to Wuhan as an impartial observer, with no conflict of interest?

They duped you by not mentioning his involvement in that research, at that site.

The alleged conflict of interest stems from the connection one of the investigators, a British zoologist and EcoHealth Alliance President Dr. Peter Daszak has with the Wuhan Institute of Virology (WIV). According to The Wall Street Journal, Dr. Daszak has worked closely with a leading virologist at WIV, Dr. Shi Zhengli on the study of bat viruses, which from 2014, was in part funded by US government grants. The institute is located just a few miles away from the wet market where Chinese authorities say SARS-CoV-2 first emerged.

What is it that you think you see there that convinces you to believe the wingnutty conspiracy theories?

 

[seminole97]

What is it that you think you see there that convinces you to believe the wingnutty conspiracy theories?

I'm not theorizing this research.
It's straight from EcoHealth's grant proposal.

https://www.ecohealthalliance.org/w...5/Text-of-Renewal-Grant-–-NIH-R01AI110964-.pdf

What do you think this experiment is trying to do:

3.3 Virus characterization: 3.3.a Construction of chimeric SARSr-CoV viruses: Infectious clones with the S gene of novel SARSr-CoVs and the SARSr-CoV WIV1 genome backbone using the reverse genetic system developed in our previous R01 (24). The correct infectious BAC clones will be screened by BAC DNA digestion with appropriate restriction enzyme or PCR amplification. The chimeric viruses will be rescued in Vero cells and then verified by sequence analyses. Our research group is well versed in coronavirus reverse genetics.
...
3.3.b Primary human airway epithelial cell culture: Primary human ciliated airway epithelial cells (HAE)cultures from the lungs of transplant recipients represent highly differentiated human airway epithelium containing ciliated and non-ciliated epithelial and goblet cells, grown on an air-liquid interface for several weeks prior to use (18, 55, 56). We will prepare HAE cultures from three different patient codes in triplicate in collaboration with the tissue procurement facility at the Cystic Fibrosis Center at UNC. Cultures will be inoculated with chimeric bat SARSr-CoVs to assess efficient replication. A
...
3.3.c Humanized mouse infection experiments: Briefly, in BSL3, n=5 10- to 20-week old hACE2 transgenic mice will be intranasally inoculated with 1 x 104 PFU of wildtype WIV-1 or chimeric bat SARSr-CoVs with different spike proteins, then monitored daily for weight loss, morbidity, and clinical signs of disease.


https://www.jax.org/strain/034860#

K18-hACE2 transgenic mice express human ACE2, the receptor used by severe acute respiratory syndrome coronavirus (SARS-CoV) to gain cellular entry. The human keratin 18 promoter directs expression to epithelia, including airway epithelia where infections typically begin. Because K18-hACE2 are susceptible to SARS-CoV-2 and SARS-CoV viruses, they are useful for studying antiviral therapies to COVID-19 and SARS.

 

[Hawk_82]

Coincidences? No. This is part of a deliberate attempt to discredit (and eventually defund or dismantle) science and honest reporting in America. Have you been living under a rock?

I know that gain of function is not just science, it is very dangerous science. I know that we would not have had the covid pandemic if not for gain of function.

It's not smart to create a disease/ virus that will kill us in hope that a lab leak never happens.

 

[Phenomenally Frantastic]

Whatever we do let’s not

Tell people cloth masks do anything to stop viral spread when they don’t.
Tell people to six feet distance because Fauci thought it “sounded good.”
Tell people the vaccine works when it doesn’t.

 

[InsaneHawkJJP]

Are you sure you don't believe in the supernatural?

I think half this country is under demonic oppression.

 

[Aardvark86]

Sounds like you're leaving the "therefore we shouldn't do anything" part for us to infer. If you don't want us to think that's your stance, you should say so clearly. Otherwise that's your stance.

mmm, no. to the extent we are to do anything, it's to prepare to react, which is mostly an issue of distribution logistics. going back to the original premise, spending a lot of money on 'predicting' and 'preventing' is pissing in the wind, because viruses are just evolutionarily smarter than we are.

 

[Rifler]

And that's it in a nut shell,.. On this, and multiple other topics, we are simply not as smart as we would like to think we are.

 

[alaskanseminole]

to prevent future pandemic.

 

[IIowaFarmBoy]

Are you sure you don't believe in the supernatural?

I think half this country is under demonic oppression.

The half that doesn't agree with you?