It's a bad matchup for Purdue. They have primarily lost to teams who like to get out in transition like Iowa, Illinois, Michigan, Indiana, and Maryland. Iowa St. will probably go small and really put pressure on their bigs just like what Iowa did. If Iowa St. isn't hot early, Purdue can stick to their plan and pound the ball down low and pick up fouls, ideally getting Niang or McKay in foul trouble. If they do that, they stand a good change at winning the game.