I'd go for the V6 myself. The V4 won't give you much power and you'll regret getting if quickly after driving off the lot. You will get better gas mileage in the V4, but its a V6 Buick, you'll still get over 20MPG with the V6 which is respectable in my opinion. I like Buick and would have pulled the trigger on an Enclave before our 3rd came along. Now I need a full size truck or a minivan. Buick makes neither.