You cannot really go wrong if you stay downtown, but staying at The Commons Hotel in the middle of campus, within view of TCF Bank Stadium would be my suggestion. I do not think any of the new hotels by the Vikings stadium will be open for a while, but the Aloft Hotel is right there, and the Depot Hotels are close. The Westin, W, Marriott, Radisson, Hyatt are all good options. A very large Embassy Suites above the Lyons pub in the Plymouth Building on Hennepin might be open by gameday. A nice Hampton in is also close to opening on Hennepin near the light rail line.
As for the Commons Hotel, this former Radisson built in the 80s while old Memorial Stadium was still standing next door, is a very large, well maintained hotel and the train platform is right outside the lobby so you are a 3 minute train ride to the Vikings Stadium, and a six minute ride away from the warehouse district and Target Field Station.
The Alumni Center ,where they have a full bar set up and food service is right next door, and even the Applebees in the hotel does not suck too much. You can also walk to Sallys, the Big Ten, Stub and Herbs, Bar Luchedor, or Buffalo Wild Wings for some pregame fun. The Campus Mall, with the Northrop Auditorium and Student Union at either end is 1.5 blocks away. There are also a slew of Asian restaurants and some other food to be found on the block
You can also visit the river flats below the student union, which is the best tailgating spot on campus for $10, or walk over the bridge to the West Bank campus as well, or all the way to the Vikings Stadium.
http://www.commonshotel.com/
http://www.vikings.com/stadium/new-stadium/webcam.html
https://www.google.com/maps/@44.971...iiSrI77nlsxctl8s-g!2e0!7i13312!8i6656!6m1!1e1
http://50.59.38.231/documents/permi...lats-Parking-U-of-M-Gopher-Football-Games.pdf