See, this is what happens every time you guys see a 30-second clip on Twitter/X without any context whatsoever and just run with it.
Trump is claiming (and feel free to disagree with him on this, as I do) that Venezuela and Mexico and other countries are sending criminals from their prisons and mental institutions to the United States. He's comparing those criminals to Hannibal Lecter, claiming these countries are sending a bunch of Hannibal Lecters to the United States.
The part where he referred to Lecter as a wonderful man is what is known as sarcasm.