ADVERTISEMENT

The return of the Woolly Mammoth

No chance in hell. Highlights as to why.

1. Incomplete genomic sequence.
2. Imperfect, if at all compatible, surrogate.
3. CRISPR technology doesn't allow for wholesale genomic edits, neither does seamless cloning.

I do this shit on a daily basis. It's good for print, buzz and fleecing stupid people of their money though. Next up, the thylacine.
 
  • Like
Reactions: Chishawk1425
How do they fund this sort of thing if the plan is to just re-introduce them into the wild?

And is re-introducing them really a good idea. Whenever you introduce a new species to an area there always seems to be unforseen side effects on the environment.
Here's a top tip. It won't work. People in the biz know this but its fun fleecing stupid people who like to burn cash.
 
  • Like
Reactions: Chishawk1425
No chance in hell. Highlights as to why.

1. Incomplete genomic sequence.
2. Imperfect, if at all compatible, surrogate.
3. CRISPR technology doesn't allow for wholesale genomic edits, neither does seamless cloning.

I do this shit on a daily basis. It's good for print, buzz and fleecing stupid people of their money though. Next up, the thylacine.
giphy.gif
 
I'm fine with trying to clone species we caused to go extinct. I figured smaller less invasive more recently extinct species would be better.

Ivory billed woodpecker
River Dolphin
Carolina parakeet

Just a few examples
 
  • Like
Reactions: WhiteSoxClone
I'm fine with trying to clone species we caused to go extinct. I figured smaller less invasive more recently extinct species would be better.

Ivory billed woodpecker
River Dolphin
Carolina parakeet

Just a few examples
They aren't sexy enough to fleece your $$$. I'm cloning neanderthal man in my lab. Come see! Bring your wads of $$$$.
 
I don't overpromise and under deliver my friend. I speak da truth. You can't make up genomic DNA that is missing. Even if you could, there are multiple things that need to happen to get out a viable clone. This is just fluff science and stealing money from rich people who have a "vested interest" in seeing if this can be done. It can't at least not in our lifetimes. But it's fun to contemplate.
 
No chance in hell. Highlights as to why.

1. Incomplete genomic sequence.
2. Imperfect, if at all compatible, surrogate.
3. CRISPR technology doesn't allow for wholesale genomic edits, neither does seamless cloning.

I do this shit on a daily basis. It's good for print, buzz and fleecing stupid people of their money though. Next up, the thylacine.

I agree, but 30-50 years from now...who knows
 
  • Like
Reactions: GOHOX69
I don't overpromise and under deliver my friend. I speak da truth. You can't make up genomic DNA that is missing. Even if you could, there are multiple things that need to happen to get out a viable clone. This is just fluff science and stealing money from rich people who have a "vested interest" in seeing if this can be done. It can't at least not in our lifetimes. But it's fun to contemplate.
 
I agree, but 30-50 years from now...who knows
Tech might advance but lost DNA is lost DNA. You might be able to guess at sequence, but once gone, it's gone. Extracting intact genomic DNA, even from living cells, is difficult, not to mention sequencing errors and artifacts are common and happen all the time. Even for singular genes, we sequence at least 5 times to make sure things are correct. Fun day dreams though. If you want to see real and sophisticated science, I could upload some crap on to youtube.

It's more feasible, by that time, to make custom organisms, rather than bring back lost ones.
 
Tech might advance but lost DNA is lost DNA. You might be able to guess at sequence, but once gone, it's gone. Extracting intact genomic DNA, even from living cells, is difficult, not to mention sequencing errors and artifacts are common and happen all the time. Even for singular genes, we sequence at least 5 times to make sure things are correct. Fun day dreams though. If you want to see real and sophisticated science, I could upload some crap on to youtube.

It's more feasible, by that time, to make custom organisms, rather than bring back lost ones.

Dude, I get that, but DNA was discovered ~70 years ago and CRISPR was discovered ~35 years ago,...... imagine what will be discovered in 35-70-140 years
 
Dude, I get that, but DNA was discovered ~70 years ago and CRISPR was discovered ~35 years ago,...... imagine what will be discovered in 35-70-140 years
CRISPR was not discovered 35 years ago. Maybe you meant to say a few years ago. I am not a Ray Kurzweil to predict the future but it's hard to fill in informational gaps, including in DNA. It's as simple as that.
 
CRISPR was not discovered 35 years ago. Maybe you meant to say a few years ago. I am not a Ray Kurzweil to predict the future but it's hard to fill in informational gaps, including in DNA. It's as simple as that.

That's what I learned in Genetics and a quick search:

The first hint of their existence came in 1987, when an unusual repetitive DNA sequence, which subsequently was defined as a CRISPR, was discovered in the Escherichia coli genome during an analysis of genes involved in phosphate metabolism.


Edit: Not the actual editing "tool"...I'll give you that
 
Last edited:
That's what I learned in Genetics and a quick search:

The first hint of their existence came in 1987, when an unusual repetitive DNA sequence, which subsequently was defined as a CRISPR, was discovered in the Escherichia coli genome during an analysis of genes involved in phosphate metabolism.

CRISPR, in its current workable form, is only a few years old. The concepts that underpin CRISPR, as you've rightly suggested, are multiple decades old. Using what they knew in 1987 would have made no difference for scientists like me in a lab doing applied science. This form of information building, until it is matured, is common in science. See for example, restriction enzymes, gibson cloning. So to say CRISPR has existed since 1987 is a real stretch. I worked in labs in 1987 and what we could do then was rudimentary at best. I mean sad by today's standards.
 
CRISPR, in its current workable form, is only a few years old. The concepts that underpin CRISPR, as you've rightly suggested, are multiple decades old. Using what they knew in 1987 would have made no difference for scientists like me in a lab doing applied science. This form of information building, until it is matured, is common in science. See for example, restriction enzymes, gibson cloning. So to say CRISPR has existed since 1987 is a real stretch. I worked in labs in 1987 and what we could do then was rudimentary at best. I mean sad by today's standards.

I said it was discovered...not always existed in current form. Kind of like continental spreading 100 years ago and plate tectonics 50-60 years ago
 
I said it was discovered...not always existed in current form
That's fine. I'll give you a point for that. And I would argue about "discovery" but you have an axe to grind so be it. I'll put this to you in simple terms. No lost creatures are going to be reanimated during your life time. Maybe your reincarnated soul will see Earth like it existed before the current ice age and deglaciation.
 
That's fine. I'll give you a point for that. And I would argue about "discovery" but you have an axe to grind so be it. I'll put this to you in simple terms. No lost creatures are going to be reanimated during your life time. Maybe your reincarnated soul will see Earth like it existed before the current ice age and deglaciation.

I agree with all of that....I'll be long dead IF it ever happens, but if there's one thing I've learned about science is that you can't ever say "never"
 
  • Haha
Reactions: GOHOX69
Not sure what to think about this. Next, T-Rex?!


I’m not sure how well you are following the science but we MIGHT if we’re lucky get enough DNA to bring back the TRex in a decade or so. They’ve found multiple pieces of fossilized dna in TRex leg bones as well as wholly or mostly intact blood vessels, connective tissue, red blood cells and most intriguingly osteoblasts (which are the Closest to stem cells and if cloned could be reverted back to stem cells). So if we get lucky and continue to find preserved soft tissue we might have enough to use Crispr to turn ostrich eggs into TRex eggs. When Jurassic Park came out it was a fantasy, now it may become reality if we continue to get lucky in our digs.

Also another thing you might have missed, but TRex wasn’t some dumb animal as shown in most depictions. Birds (ie dinosaurs that survived the Cretaceous extinction event) are actually smarter than mammals with similarly sized brains (ie think about Corvids And parrots being as smart or smarter than far larger brained monkeys. So the TRex was likely at least as smart as baboon, probably as smart as orangutans and possibly as smart as humans. Scientists are even questioning, if TRexes would have had a sophisticated culture.
 
Last edited:

Unless you are 100% African from central and Southern Africa, you have at least a portion of Neanderthal DNA in you. If you’ve got some Asian or Native American ancestry you likely also have even more primitive Erectus and/or Denisovan dna as well. Basically when Homo Sapiens ran into another human species it raped, murdered and maybe cannibalized them.
 
  • Like
Reactions: fsu1jreed
Does anyone think this is fluff science, and just a way to extract money from stupid people? Anyone on this board an expert?
 
  • Like
Reactions: GOHOX69
Does anyone think this is fluff science, and just a way to extract money from stupid people? Anyone on this board an expert?
No, I only do this for a living. 1000% possible. Send me money via venmo.
 
ADVERTISEMENT
ADVERTISEMENT