I don't think they're real, but I think it's possible. I'm not sure the "never found a body" or never gotten video aspect holds up to me. As others have mentioned, people have no idea just how vast and untouched the wilderness is in parts of this country and Canada. But in addition, even when there are people, the wilderness is incredibly dense.
It's not uncommon at all for hikers to get a very little ways off the trail, and never be found again. The body can't be found, close off a common trail, and even having a relatively small area to search in and hundreds of searchers.
Or hikers who have died of thirst or hypothermia, and they are found just like a mile off a major trail or civilization, but they weren't able to find their way out. The denseness and enveloping aspect of the wilderness is just not appreciated.
The biggest argument against it is probably the estimation of how large the community would need to be for genetic diversity. If you believe a bigfoot community could thrive with about 50 members, then yeah I think it's totally plausible for them to go unseen in North America. But I think most estimates are more like 500-1000 in a community to thrive. To me, that starts to push it. Based on large primates, the amount of food required for 1000+ bigfoots seems to stretch the possibility that they could exist for so long without proof. Especially if you figure that you'd think over time they'd either have boom periods where their population exploded, in which they'd be more likely to be discovered, or decline to the point of not having the genetic diversity to survive.
I do think the vast majority of sightings are false, as they take place in areas that are way too populated for a community to survive in great enough numbers to be undiscovered.