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Cannabis and Covid

When comparing cannabis users to non-users, the researchers determined that cannabis users “were younger and had higher prevalence of tobacco use.” Among the patients who did not use cannabis, “other comorbidities including obstructive sleep apnea, obesity, hypertension, and diabetes mellitus were more prevalent.”


Sounds like a real apples to apples scientific comparison derp!
 
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When comparing cannabis users to non-users, the researchers determined that cannabis users “were younger and had higher prevalence of tobacco use.” Among the patients who did not use cannabis, “other comorbidities including obstructive sleep apnea, obesity, hypertension, and diabetes mellitus were more prevalent.”


Sounds like a real apples to apples scientific comparison derp!

Yup

If they did not adjust for those demographic differences, it's really a nonsense conclusion.
 
drunk rob riggle GIF by Son of Zorn
 
There are cannabinoid receptors in the immune system, fwiw
Interesting. I just ran across this article today re: cannabinoid receptors, acetaminophen and autism.

Although acetaminophen has been used as an anal-gesic for more than a hundred years, its mechanism of action has remained elusive. It has recently been shown by two independent groups (Hogestatt et al. 2005, Bertolini et al. 2006) that acetaminophen produces analgesia by potentiating cannabinoid receptors in the brain. These observations have been confirmed by Mallet and colleagues (2008).Hogestatt and colleagues have shown that acetamin-ophen is deacetylated to p-aminophenol which is con-jugated with arachidonic acid in the brain and spinal cord by fatty acid amide hydrolase (FAAH). The result-ing compound, N-arachidonoylphenolamine inhibits the cellular uptake of anandamide, a naturally occur-ring endogenous cannabinoid or endocannabinoid. The result is increased levels of endocannabinoids which produce an analgesic effect (Hogestatt et al. 2005). Bertolini and colleagues (2006) noticed a similarity in the effect of acetaminophen and cannabinoids. Cannabinoids and acetaminophen both have an anal-gesic action and lower body temperature. They were able to show that blockage of cannabinoid receptor 1 (CB1) completely prevents the analgesic activity of acetaminophen (Bertolini et al. 2006).

 
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